Finish the game with the lowest score. There is a card with a score in the middle of the table; each player can refuse to take the card by placing one of their chips in the middle. Your supply of chips is limited, but if you pick up the card you add any chips placed to your supply.
In addition any card that is part of a number run on you existing card does not count to your final score, so sometimes instead of no thanks, you’ll be going “Yes Please!”